During the first phase of COSYS-Med, the actions undertaken made it possible to establish solid links between the various North (MIO and MARBEC) and South (CBS, FSB and INAT) partners on a new issue for the IRD in this region. The logic proposed was based on a “project” approach around three thematic axes, research, training and transfer, the research axis being itself subdivided into four work-packages (Measure, Evaluate, Explain/Predict and Remedy). The first phase made it possible to create a consortium of researchers capable of proposing and setting up multidisciplinary projects with the support of national and international donors with real dynamism (21 projects submitted, 48 co-publications).